InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ALPI

Summary

InnateDB Protein

IDBP-83247.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ALPI

Protein Name

alkaline phosphatase, intestinal

Synonyms

IAP;

Species

Homo sapiens

Ensembl Protein

ENSP00000295463

InnateDB Gene

IDBG-83245 (ALPI)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cell membrane; Lipid-anchor, GPI-anchor.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0002020	protease binding
GO:0003824	catalytic activity
GO:0004035	alkaline phosphatase activity
GO:0008270	zinc ion binding
GO:0016791	phosphatase activity

Biological Process

GO:0008152	metabolic process
GO:0016311	dephosphorylation

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0031225	anchored component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001952 Alkaline phosphatase
IPR017850 Alkaline-phosphatase-like, core domain

PFAM

PF00245

PRINTS

PR00113

PIRSF

SMART

SM00098

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P09923

PhosphoSite

PhosphoSite-P09923

TrEMBL

A0A024R4A2

UniProt Splice Variant

Entrez Gene

248

UniGene

Hs.37009

RefSeq

NP_001622

HUGO

HGNC:437

OMIM

171740

CCDS

CCDS2492

HPRD

01376

IMGT

EMBL

AC068134 AK313163 BC132678 CH471063 J03930 M15694 M19161 M31008 Y00512

GenPept

AAA51703 AAA51704 AAA51705 AAA98617 AAI32679 AAY24089 BAG35981 CAA68564 EAW70997 EAW70998