InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SIX4

Summary

InnateDB Protein

IDBP-8329.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SIX4

Protein Name

SIX homeobox 4

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000216513

InnateDB Gene

IDBG-8327 (SIX4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0007519	skeletal muscle tissue development
GO:0008582	regulation of synaptic growth at neuromuscular junction
GO:0009653	anatomical structure morphogenesis
GO:0010468	regulation of gene expression
GO:0032880	regulation of protein localization
GO:0042472	inner ear morphogenesis
GO:0043524	negative regulation of neuron apoptotic process
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048538	thymus development
GO:0048699	generation of neurons
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0048704	embryonic skeletal system morphogenesis
GO:0048856	anatomical structure development
GO:0051451	myoblast migration
GO:0072075	metanephric mesenchyme development
GO:0072095	regulation of branch elongation involved in ureteric bud branching
GO:0072107	positive regulation of ureteric bud formation
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis