Version 5.4
Homo sapiens Protein: AKAP14
Summary
InnateDB Protein IDBP-84129.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKAP14
Protein Name A kinase (PRKA) anchor protein 14
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000360485
InnateDB Gene IDBG-84127 (AKAP14)
Protein Structure
UniProt Annotation
Function Binds to type II regulatory subunits of protein kinase A and anchors/targets them.
Subcellular Localization Cytoplasm {ECO:0000305}.
Disease Associations
Tissue Specificity Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia. {ECO:0000269PubMed:12475942}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0051018 protein kinase A binding
Biological Process
GO:0007283 spermatogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0035686 sperm fibrous sheath
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86UN6
PhosphoSite PhosphoSite-Q86UN6
TrEMBL
UniProt Splice Variant
Entrez Gene 158798
UniGene Hs.592245
RefSeq NP_848928
HUGO HGNC:24061
OMIM 300462
CCDS CCDS14591
HPRD 02353
IMGT
EMBL AF514780 AF514781 AF514782 BC066357
GenPept AAH66357 AAP20825 AAP20826 AAP20827

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca