InnateDB Protein
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IDBP-84382.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ATP1B4
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Protein Name
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ATPase, Na+/K+ transporting, beta 4 polypeptide
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000355346
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InnateDB Gene
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IDBG-84378 (ATP1B4)
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Protein Structure
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Function |
May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit. {ECO:0000269PubMed:17592128}.
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Subcellular Localization |
Nucleus inner membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Detected in nuclear envelops. {ECO:0000269PubMed:14656723, ECO:0000269PubMed:17592128}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in skeletal muscle and at a lower level in heart. {ECO:0000269PubMed:10456317}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0015077
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monovalent inorganic cation transmembrane transporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000402
Sodium/potassium-transporting ATPase subunit beta
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PFAM |
PF00287
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UN42
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
23439
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UniGene |
Hs.292599
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RefSeq |
NP_036201
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HUGO |
HGNC:808
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OMIM |
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CCDS |
CCDS14598
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HPRD |
06453
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IMGT |
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EMBL |
AF158383
AF158384
BC117227
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GenPept |
AAD49692
AAD49693
AAI17228
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