InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ASB1

Summary

InnateDB Protein

IDBP-84558.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ASB1

Protein Name

ankyrin repeat and SOCS box containing 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000264607

InnateDB Gene

IDBG-84556 (ASB1)

Protein Structure

UniProt Annotation

Function

May play a role in testis development (By similarity). Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250, ECO:0000269PubMed:16325183}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	23 [view]
Protein-Protein	21 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0016567	protein ubiquitination
GO:0030539	male genitalia development
GO:0035556	intracellular signal transduction
GO:0042036	negative regulation of cytokine biosynthetic process