InnateDB Protein
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IDBP-84648.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SDF4
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Protein Name
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stromal cell derived factor 4
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000353094
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InnateDB Gene
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IDBG-84646 (SDF4)
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Protein Structure
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Function |
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. {ECO:0000250}.Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.
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Subcellular Localization |
Isoform 1: Golgi apparatus lumen {ECO:0000250}.Isoform 5: Cytoplasm. Cell projection, bleb. Note=Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Isoform 5 is expressed in pancreas. {ECO:0000269PubMed:17442889}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
27
[view]
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Protein-Protein |
27
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002048
EF-hand domain
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PFAM |
PF00036
PF13202
PF13405
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PRINTS |
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PIRSF |
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SMART |
SM00054
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BRK5
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PhosphoSite |
PhosphoSite-Q9BRK5
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TrEMBL |
A0A024R084
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UniProt Splice Variant |
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Entrez Gene |
51150
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UniGene |
Hs.42806
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RefSeq |
NP_057260
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HUGO |
HGNC:24188
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OMIM |
614282
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CCDS |
CCDS30553
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HPRD |
13113
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IMGT |
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EMBL |
AF132749
AF153686
AF178986
AK027277
AK075352
AK222521
AK223079
AK299810
AK315517
AL162741
BC006211
BC007625
BC008917
BC011244
BC022375
CH471183
L79912
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GenPept |
AAD51612
AAF44350
AAH06211
AAH07625
AAH08917
AAH11244
AAH22375
AAL40084
AAL75950
BAB55012
BAC11563
BAD96241
BAD96799
BAG37898
BAG61683
CAI23251
CAI23252
EAW56272
EAW56273
EAW56274
EAW56277
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