Version 5.4
Homo sapiens Gene: SDF4
Summary
InnateDB Gene IDBG-84646.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SDF4
Gene Name stromal cell derived factor 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000078808
Encoded Proteins
IDBP-84648
stromal cell derived factor 4
IDBP-84650
stromal cell derived factor 4
IDBP-293469
stromal cell derived factor 4
IDBP-599606
stromal cell derived factor 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:1216908-1232031
Strand Reverse strand
Band p36.33
Transcripts
ENST00000360001 ENSP00000353094
ENST00000263741 ENSP00000263741
ENST00000403997 ENSP00000384207
ENST00000465727 ENSP00000435962
ENST00000494748
ENST00000478938
ENST00000459994
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0009650 UV protection
GO:0017156 calcium ion-dependent exocytosis
GO:0021549 cerebellum development
GO:0045444 fat cell differentiation
GO:0045471 response to ethanol
GO:0070625 zymogen granule exocytosis
Cellular Component
GO:0005737 cytoplasm
GO:0005770 late endosome
GO:0005794 Golgi apparatus
GO:0005796 Golgi lumen
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032059 bleb
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029076
View Gene Order
ENSBTAG00000015642
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.42806
RefSeq NM_016176 NM_016547
HUGO
OMIM
CCDS CCDS12 CCDS30553
HPRD 13113
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca