Version 5.4
Homo sapiens Protein: MIB2
Summary
InnateDB Protein IDBP-85555.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MIB2
Protein Name mindbomb homolog 2 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367984
InnateDB Gene IDBG-85549 (MIB2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0004842 ubiquitin-protein transferase activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0007219 Notch signaling pathway
GO:0016567 protein ubiquitination
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000433 Zinc finger, ZZ-type
IPR002110 Ankyrin repeat
IPR010606 Mib-herc2
IPR020683 Ankyrin repeat-containing domain
PFAM PF00569
PF00023
PF13606
PF06701
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00291
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96AX9
PhosphoSite PhosphoSite-Q96AX9
TrEMBL D6RFJ2
UniProt Splice Variant
Entrez Gene 142678
UniGene Hs.135805
RefSeq NP_001164160
HUGO HGNC:30577
OMIM 611141
CCDS CCDS53264
HPRD 15905
IMGT
EMBL AB064367 AB074480 AB076691 AB076692 AB076693 AB097000 AK091610 AK095914 AK096295 AK097106 AK098785 AK122751 AK122863 AK128167 AK302757 AL691432 AL834527 BC016490 BC037542
GenPept AAH16490 AAH37542 BAB82979 BAB92950 BAC00992 BAC00993 BAC00994 BAC03707 BAC04646 BAC04752 BAC04952 BAC05413 BAC77353 BAG53705 BAG53766 BAG54643 BAG63969 CAD39183

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca