Homo sapiens Protein: CRTAC1
Summary
InnateDB Protein IDBP-85776.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRTAC1
Protein Name cartilage acidic protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359629
InnateDB Gene IDBG-85774 (CRTAC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted, extracellular space, extracellular matrix {ECO:0000269PubMed:17074475}.
Disease Associations
Tissue Specificity Expressed in the interterritorial matrix of articular deep zone cartilage (at protein level). Isoform 1 and isoform 2 are expressed in brain. Isoform 1 is detected in lung and chondrocytes. Detected in cartilage, bone, cultured chondrocytes and lung, and at low levels in heart. Not detected in osteoblasts. {ECO:0000269PubMed:11139377, ECO:0000269PubMed:17074475}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
Cellular Component
GO:0005578 proteinaceous extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR001881 EGF-like calcium-binding domain
IPR011519 ASPIC/UnbV
IPR013517 FG-GAP repeat
PFAM PF07645
PF07593
PF01839
PF14312
PRINTS
PIRSF
SMART SM00179
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NQ79
PhosphoSite PhosphoSite-Q9NQ79
TrEMBL
UniProt Splice Variant
Entrez Gene 55118
UniGene Hs.500736
RefSeq NP_060528
HUGO HGNC:14882
OMIM 606276
CCDS CCDS31266
HPRD 10447
IMGT
EMBL AJ276171 AJ279016 AJ421515 AK001182 AK292084 AL139239 AL358938 BC034245
GenPept AAH34245 BAA91540 BAF84773 CAB98267 CAB98268 CAB98269 CAC08451 CAD13394 CAI12584 CAI12585 CAI14277