Version 5.4
Homo sapiens Protein: KCNK16
Summary
InnateDB Protein IDBP-86200.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNK16
Protein Name potassium channel, subfamily K, member 16
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362324
InnateDB Gene IDBG-86196 (KCNK16)
Protein Structure
UniProt Annotation
Function Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Highly expressed in pancreas. Not detectable in the other tissues tested. {ECO:0000269PubMed:12724142}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005244 voltage-gated ion channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003280 Two pore domain potassium channel
IPR005821 Ion transport domain
IPR013099 Two pore domain potassium channel domain
PFAM PF00520
PF07885
PRINTS PR01333
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96T55
PhosphoSite PhosphoSite-Q96T55
TrEMBL D6RC57
UniProt Splice Variant
Entrez Gene 83795
UniGene Hs.287765
RefSeq NP_001128579
HUGO HGNC:14464
OMIM 607369
CCDS CCDS47420
HPRD 09565
IMGT
EMBL AF358909 AL136087 AY253145 AY253146 AY253147 BC111860 CH471081 EU978943
GenPept AAI11861 AAK49532 AAP82866 AAP82867 AAP82868 ACH86102 CAI19537 EAX03982 EAX03984 EAX03985

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca