Version 5.4
Homo sapiens Protein: SH2D3C
Summary
InnateDB Protein IDBP-86378.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH2D3C
Protein Name SH2 domain containing 3C
Synonyms CHAT; NSP3; PRO34088; SHEP1;
Species Homo sapiens
Ensembl Protein ENSP00000362373
InnateDB Gene IDBG-86372 (SH2D3C)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 11 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0007264 small GTPase mediated signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000980 SH2 domain
IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
IPR023578 Ras guanine nucleotide exchange factor domain
PFAM PF00017
PF14633
PF00617
PRINTS PR00401
PIRSF
SMART SM00252
SM00147
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B3KUE2
UniProt Splice Variant
Entrez Gene 10044
UniGene Hs.306412
RefSeq NP_001239263
HUGO HGNC:16884
OMIM 604722
CCDS CCDS59145
HPRD 05284
IMGT
EMBL AK096983
GenPept BAG53404

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca