Version 5.4
Homo sapiens Protein: FOXP4
Summary
InnateDB Protein IDBP-86671.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FOXP4
Protein Name forkhead box P4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362148
InnateDB Gene IDBG-86663 (FOXP4)
Protein Structure
UniProt Annotation
Function Transcriptional repressor that represses lung-specific expression. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00089}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001766 Transcription factor, fork head
PFAM PF00250
PRINTS PR00053
PIRSF
SMART SM00339
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IVH2
PhosphoSite PhosphoSite-Q8IVH2
TrEMBL Q8N4A5
UniProt Splice Variant
Entrez Gene 116113
UniGene Hs.603717
RefSeq NP_001012427
HUGO HGNC:20842
OMIM 608924
CCDS CCDS34448
HPRD 10600
IMGT
EMBL AB080747 AL139331 AL832437 BC013030 BC034931 BC040962 BC052803 CH471081
GenPept AAH13030 AAH34931 AAH40962 AAH52803 BAC53809 CAH10652 CAH72540 CAH72541 CAH72542 EAX04047 EAX04048 EAX04049

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca