InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TFEB

Summary

InnateDB Protein

IDBP-86799.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TFEB

Protein Name

transcription factor EB

Synonyms

ALPHATFEB; BHLHE35; TCFEB;

Species

Homo sapiens

Ensembl Protein

ENSP00000343948

InnateDB Gene

IDBG-86793 (TFEB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0044212	transcription regulatory region DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0001892	embryonic placenta development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006914	autophagy
GO:0006959	humoral immune response
GO:0007040	lysosome organization
GO:0010508	positive regulation of autophagy
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter