InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: USP49

Summary

InnateDB Protein

IDBP-86913.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

USP49

Protein Name

ubiquitin specific peptidase 49

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000362101

InnateDB Gene

IDBG-86911 (USP49)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.

Experimentally validated
Total	47 [view]
Protein-Protein	47 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008234	cysteine-type peptidase activity
GO:0008270	zinc ion binding
GO:0036459	ubiquitinyl hydrolase activity

Biological Process

GO:0006511

ubiquitin-dependent protein catabolic process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR001607 Zinc finger, UBP-type
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain

PFAM

PF00443
PF02148

PRINTS

PIRSF

SMART

SM00290

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q5T3E1

UniProt Splice Variant

Entrez Gene

25862

UniGene

Hs.665742

RefSeq

HUGO

HGNC:20078

OMIM

CCDS

HPRD

10075

IMGT

EMBL

AL160163 AL365205

GenPept