Version 5.4
Homo sapiens Gene: USP49
Summary
InnateDB Gene IDBG-86911.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP49
Gene Name ubiquitin specific peptidase 49
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164663
Encoded Proteins
IDBP-86913
ubiquitin specific peptidase 49
IDBP-86915
ubiquitin specific peptidase 49
IDBP-86917
ubiquitin specific peptidase 49
IDBP-241960
ubiquitin specific peptidase 49
IDBP-378486
ubiquitin specific peptidase 49
IDBP-378494
ubiquitin specific peptidase 49
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:41789896-41895361
Strand Reverse strand
Band p21.1
Transcripts
ENST00000373010 ENSP00000362101
ENST00000373009 ENSP00000362100
ENST00000373006 ENSP00000362097
ENST00000394253 ENSP00000377797
ENST00000448078 ENSP00000389842
ENST00000423567 ENSP00000411603
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
Experimentally validated
Total 47 [view]
Protein-Protein 47 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004197 cysteine-type endopeptidase activity
GO:0004221 ubiquitin thiolesterase activity
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
GO:0008270 zinc ion binding
GO:0036459 ubiquitinyl hydrolase activity
GO:0042393 histone binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination
GO:0035616 histone H2B conserved C-terminal lysine deubiquitination
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000090115
View Gene Order
ENSBTAG00000008981
Not yet available
Cross-References
SwissProt
TrEMBL A6PVU2 Q5T3E1
UniProt Splice Variant
Entrez Gene 25862
UniGene Hs.593575 Hs.610697 Hs.665742
RefSeq NM_001286554 NM_018561
HUGO HGNC:20078
OMIM
CCDS CCDS4861 CCDS69111
HPRD 10075
IMGT
EMBL AL160163 AL365205
GenPept
RNA Seq Atlas 25862

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca