Version 5.4
Homo sapiens Protein: DFFB
Summary
InnateDB Protein IDBP-86960.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DFFB
Protein Name DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
Synonyms CAD; CPAN; DFF-40; DFF2; DFF40;
Species Homo sapiens
Ensembl Protein ENSP00000345906
InnateDB Gene IDBG-86952 (DFFB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR003508 CIDE-N domain
PFAM PF02017
PRINTS
PIRSF
SMART SM00266
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q96P72
UniProt Splice Variant
Entrez Gene 1677
UniGene Hs.133089
RefSeq
HUGO HGNC:2773
OMIM 601883
CCDS
HPRD 03532
IMGT
EMBL AF409062 AL691523
GenPept AAL02007

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca