InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SET

Summary

InnateDB Protein

IDBP-88490.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SET

Protein Name

SET nuclear oncogene

Synonyms

2PP2A; I2PP2A; IGAAD; IPP2A2; PHAPII; TAF-I; TAF-IBETA;

Species

Homo sapiens

Ensembl Protein

ENSP00000361773

InnateDB Gene

IDBG-88484 (SET)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 149 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.

Experimentally validated
Total	149 [view]
Protein-Protein	147 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	36 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0004864	protein phosphatase inhibitor activity
GO:0005515	protein binding
GO:0008601	protein phosphatase type 2A regulator activity
GO:0042393	histone binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0006260	DNA replication
GO:0006334	nucleosome assembly
GO:0006337	nucleosome disassembly
GO:0006913	nucleocytoplasmic transport
GO:0010467	gene expression
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0035067	negative regulation of histone acetylation
GO:0043086	negative regulation of catalytic activity
GO:0043524	negative regulation of neuron apoptotic process
GO:0045892	negative regulation of transcription, DNA-templated
GO:0050790	regulation of catalytic activity

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0043234	protein complex
GO:0048471	perinuclear region of cytoplasm