Homo sapiens Protein: FBXO44
Summary
InnateDB Protein IDBP-89451.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXO44
Protein Name F-box protein 44
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000251547
InnateDB Gene IDBG-89443 (FBXO44)
Protein Structure
UniProt Annotation
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.
Subcellular Localization
Disease Associations
Tissue Specificity Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver. {ECO:0000269PubMed:12383498}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0019005 SCF ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR001810 F-box domain
IPR007397 F-box associated (FBA) domain
IPR008979 Galactose-binding domain-like
PFAM PF00646
PF12937
PF13013
PF04300
PRINTS
PIRSF
SMART SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H4M3
PhosphoSite PhosphoSite-
TrEMBL B7Z1X4
UniProt Splice Variant
Entrez Gene 93611
UniGene Hs.556006
RefSeq NP_149438
HUGO HGNC:24847
OMIM 609111
CCDS CCDS132
HPRD 16445
IMGT
EMBL AK055344 AK294053 AK301418 AK316284 AL031731 AY007380 AY040878 BC007832 CH471130 CR749368
GenPept AAG09623 AAH07832 AAK77940 BAG51504 BAH11660 BAH13479 BAH14655 CAH18221 CAI20210 CAI20211 CAI20212 CAI20213 EAW71690 EAW71691 EAW71692 EAW71695