Version 5.4
Homo sapiens Protein: RCAN2
Summary
InnateDB Protein IDBP-89841.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RCAN2
Protein Name regulator of calcineurin 2
Synonyms CSP2; DSCR1L1; MCIP2; RCN2; ZAKI-4; ZAKI4;
Species Homo sapiens
Ensembl Protein ENSP00000305223
InnateDB Gene IDBG-89839 (RCAN2)
Protein Structure
UniProt Annotation
Function Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
Biological Process
GO:0019722 calcium-mediated signaling
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID
InterPro IPR006931 Calcipressin
PFAM PF04847
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14206
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 10231
UniGene Hs.440168
RefSeq NP_001238902
HUGO HGNC:3041
OMIM 604876
CCDS CCDS59023
HPRD 05342
IMGT
EMBL AK090990 AL359633 AL390741 AY034085 AY034086 CH471081 D83407
GenPept AAK59805 AAK59806 BAA11911 BAG52258 CAH73259 CAH73260 CAI16754 EAX04294

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca