Version 5.4
Homo sapiens Protein: NPPA
Summary
InnateDB Protein IDBP-89857.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPPA
Protein Name natriuretic peptide A
Synonyms ANF; ANP; ATFB6; ATRST2; CDD-ANF; PND;
Species Homo sapiens
Ensembl Protein ENSP00000365659
InnateDB Gene IDBG-89853 (NPPA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0050880 regulation of blood vessel size
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000663 Natriuretic peptide
IPR002407 Natriuretic peptide, atrial type
IPR002408 Natriuretic peptide, brain type
PFAM PF00212
PRINTS PR00710
PR00711
PR00712
PIRSF
SMART SM00183
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B0ZBE8
UniProt Splice Variant
Entrez Gene 4878
UniGene
RefSeq
HUGO HGNC:7939
OMIM 108780
CCDS
HPRD 00164
IMGT
EMBL AL021155 EU326308
GenPept ACA05915

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca