InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PNLIP

Summary

InnateDB Protein

IDBP-90645.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PNLIP

Protein Name

pancreatic lipase

Synonyms

PL; PNLIPD; PTL;

Species

Homo sapiens

Ensembl Protein

ENSP00000358223

InnateDB Gene

IDBG-90643 (PNLIP)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004806	triglyceride lipase activity
GO:0005515	protein binding
GO:0046872	metal ion binding
GO:0052689	carboxylic ester hydrolase activity

Biological Process

GO:0001523	retinoid metabolic process
GO:0006629	lipid metabolic process
GO:0007603	phototransduction, visible light
GO:0016042	lipid catabolic process
GO:0030299	intestinal cholesterol absorption
GO:0044241	lipid digestion
GO:0044281	small molecule metabolic process

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

InterPro

IPR000734 Lipase
IPR001024 PLAT/LH2 domain
IPR002331 Pancreatic lipase
IPR008976 Lipase/lipooxygenase, PLAT/LH2
IPR013818 Lipase, N-terminal
IPR016272 Lipoprotein lipase, LIPH
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF01477
PF00151

PRINTS

PR00821
PR00823

PIRSF

PIRSF000865

SMART

SM00308

TIGRFAMs

Post-translational Modifications

Modification

Cross-References