InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BMP5

Summary

InnateDB Protein

IDBP-91209.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BMP5

Protein Name

bone morphogenetic protein 5

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000359866

InnateDB Gene

IDBG-91207 (BMP5)

Protein Structure

UniProt Annotation

Function

Induces cartilage and bone formation.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Expressed in the lung and liver.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0070700	BMP receptor binding

Biological Process

GO:0001501	skeletal system development
GO:0001503	ossification
GO:0003323	type B pancreatic cell development
GO:0007389	pattern specification process
GO:0008285	negative regulation of cell proliferation
GO:0010719	negative regulation of epithelial to mesenchymal transition
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010894	negative regulation of steroid biosynthetic process
GO:0030539	male genitalia development
GO:0032348	negative regulation of aldosterone biosynthetic process
GO:0040007	growth
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050679	positive regulation of epithelial cell proliferation
GO:0051216	cartilage development
GO:0071676	negative regulation of mononuclear cell migration
GO:1900006	positive regulation of dendrite development
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000065	negative regulation of cortisol biosynthetic process
GO:2000105	positive regulation of DNA-dependent DNA replication