InnateDB Protein
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IDBP-92086.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SMAP1
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Protein Name
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small ArfGAP 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000359481
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InnateDB Gene
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IDBG-92082 (SMAP1)
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Protein Structure
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Function |
GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Detected in bone marrow, adrenal gland, trachea, lymph node, spinal cord, peripheral blood leukocytes, thyroid and stomach. {ECO:0000269PubMed:12119110}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
8
[view]
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Protein-Protein |
8
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001164
Arf GTPase activating protein
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PFAM |
PF01412
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PRINTS |
PR00405
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PIRSF |
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SMART |
SM00105
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TIGRFAMs |
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Modification |
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SwissProt |
Q8IYB5
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PhosphoSite |
PhosphoSite-Q8IYB5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
60682
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UniGene |
Hs.485717
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RefSeq |
NP_001268368
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HUGO |
HGNC:19651
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OMIM |
611372
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CCDS |
CCDS64459
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HPRD |
18072
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IMGT |
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EMBL |
AF442495
AK023221
AK222711
AL121961
AL354943
AL591049
AL833906
AY055003
AY055004
AY055005
AY055006
AY055007
AY055008
AY055009
AY055010
AY055011
AY055012
AY055013
AY055014
AY055015
BC008672
BC028074
BC036123
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GenPept |
AAH08672
AAH28074
AAH36123
AAL14714
AAL14715
AAL14716
AAL14717
AAP97320
BAB14473
BAD96431
CAD38762
CAI12310
CAI12311
CAI12312
CAI14240
CAI14241
CAI14242
CAI42146
CAI42147
CAI42148
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