Version 5.4
Homo sapiens Gene: SMAP1
Summary
InnateDB Gene IDBG-92082.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMAP1
Gene Name small ArfGAP 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112305
Encoded Proteins
IDBP-92084
small ArfGAP 1
IDBP-92086
small ArfGAP 1
IDBP-92088
small ArfGAP 1
IDBP-382837
small ArfGAP 1
IDBP-382842
small ArfGAP 1
IDBP-813647
small ArfGAP 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human gene product is also a type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:70667776-70862015
Strand Forward strand
Band q13
Transcripts
ENST00000370455 ENSP00000359484
ENST00000370452 ENSP00000359481
ENST00000316999 ENSP00000313382
ENST00000445046 ENSP00000415426
ENST00000439432 ENSP00000398306
ENST00000619054 ENSP00000484538
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0030276 clathrin binding
Biological Process
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0045648 positive regulation of erythrocyte differentiation
GO:2000369 regulation of clathrin-mediated endocytosis
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026155
View Gene Order
ENSBTAG00000038190
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 60682
UniGene
RefSeq NM_001281440 NM_001044305 NM_001281439 NM_021940
HUGO HGNC:19651
OMIM 611372
CCDS CCDS75478 CCDS43478 CCDS4973 CCDS64459
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 60682

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca