InnateDB Protein
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IDBP-92745.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PHPT1
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Protein Name
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phosphohistidine phosphatase 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000360724
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InnateDB Gene
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IDBG-92741 (PHPT1)
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Protein Structure
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|
Function |
Exhibits phosphohistidine phosphatase activity.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed abundantly in heart and skeletal muscle.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
13
[view]
|
Protein-Protein |
12
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0006470
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protein dephosphorylation
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GO:0035971
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peptidyl-histidine dephosphorylation
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GO:0050860
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negative regulation of T cell receptor signaling pathway
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GO:0051350
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negative regulation of lyase activity
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GO:2000147
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positive regulation of cell motility
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GO:2000249
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regulation of actin cytoskeleton reorganization
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GO:2000984
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negative regulation of ATP citrate synthase activity
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Cellular Component |
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PDB ID |
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InterPro |
IPR007702
Janus
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PFAM |
PF05005
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NRX4
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PhosphoSite |
PhosphoSite-Q9NRX4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
29085
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UniGene |
|
RefSeq |
NP_001274272
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HUGO |
HGNC:30033
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OMIM |
610167
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CCDS |
CCDS48060
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HPRD |
17849
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IMGT |
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EMBL |
AF164795
AF285119
AF393504
AL136644
AL355987
BC024648
BQ922335
CH471090
|
GenPept |
AAF80759
AAG01156
AAH24648
AAN52504
CAB66579
CAI12692
CAI12693
EAW88289
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