Version 5.4
Homo sapiens Protein: IMPG1
Summary
InnateDB Protein IDBP-93259.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMPG1
Protein Name interphotoreceptor matrix proteoglycan 1
Synonyms GP147; IPM150; SPACR;
Species Homo sapiens
Ensembl Protein ENSP00000358966
InnateDB Gene IDBG-93251 (IMPG1)
Protein Structure
UniProt Annotation
Function May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix. {ECO:0000269PubMed:9813076}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Abundantly expressed in retina where it is specifically expressed by cone and rod photoreceptor cells. Localizes to cone and rod photoreceptor cells surrounding the interphotoreceptor matrix of the retina. {ECO:0000269PubMed:10601738, ECO:0000269PubMed:9719680, ECO:0000269PubMed:9813076}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005201 extracellular matrix structural constituent
GO:0005515 protein binding
Biological Process
GO:0007601 visual perception
Cellular Component
GO:0005578 proteinaceous extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR000082 SEA domain
IPR000742 Epidermal growth factor-like domain
PFAM PF01390
PF00008
PRINTS
PIRSF
SMART SM00200
SM00181
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q17R60
PhosphoSite PhosphoSite-Q17R60
TrEMBL H0UI08
UniProt Splice Variant
Entrez Gene 3617
UniGene Hs.590893
RefSeq NP_001554
HUGO HGNC:6055
OMIM 602870
CCDS CCDS4985
HPRD 04186
IMGT
EMBL AF017760 AF017761 AF017762 AF017763 AF017764 AF017765 AF017766 AF017767 AF017768 AF017769 AF017770 AF017771 AF017772 AF017773 AF017774 AF017775 AF017776 AF047492 AL356962 AL392166 BC117450 BC117452 CH471051
GenPept AAC03789 AAC68835 AAI17451 AAI17453 CAC36327 CAI41298 EAW48725 EAW48726 EAW48727

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca