InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NT5E

Summary

InnateDB Protein

IDBP-93987.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NT5E

Protein Name

5'-nucleotidase, ecto (CD73)

Synonyms

CALJA; CD73; E5NT; eN; eNT; NT; NT5; NTE;

Species

Homo sapiens

Ensembl Protein

ENSP00000358660

InnateDB Gene

IDBG-93979 (NT5E)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0016787	hydrolase activity
GO:0016788	hydrolase activity, acting on ester bonds
GO:0046872	metal ion binding

Biological Process

GO:0009166

nucleotide catabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR006179 5\'-Nucleotidase/apyrase
IPR029052 Metallo-dependent phosphatase-like

PFAM

PF00149

PRINTS

PR01607

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q96B60

UniProt Splice Variant

Entrez Gene

4907

UniGene

Hs.631187

RefSeq

HUGO

HGNC:8021

OMIM

129190

CCDS

HPRD

00552

IMGT

EMBL

AL135903 AL589666 BC015940 CH471051

GenPept

AAH15940 EAW48636