Version 5.4
Homo sapiens Protein: CGA
Summary
InnateDB Protein IDBP-94100.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CGA
Protein Name glycoprotein hormones, alpha polypeptide
Synonyms CG-ALPHA; FSHA; GPHa; GPHA1; HCG; LHA; TSHA;
Species Homo sapiens
Ensembl Protein ENSP00000358595
InnateDB Gene IDBG-94098 (CGA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008284 positive regulation of cell proliferation
GO:0016486 peptide hormone processing
GO:0030335 positive regulation of cell migration
GO:0044267 cellular protein metabolic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000476 Glycoprotein hormone alpha chain
IPR029034 Cystine-knot cytokine
PFAM PF00236
PRINTS PR00274
PIRSF
SMART SM00067
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P01215
PhosphoSite PhosphoSite-P01215
TrEMBL Q6I9S8
UniProt Splice Variant
Entrez Gene 1081
UniGene
RefSeq NP_000726
HUGO HGNC:1885
OMIM 118850
CCDS CCDS5007
HPRD 00342
IMGT
EMBL AK311972 BC020782 BC055080 CH471051 CR457427 EU081886 FJ624078 FJ624079 J00150 J00151 J00152 S70583 S70584 S70585 V00518
GenPept AAB30827 AAD13690 AAH20782 AAH55080 ABU96751 ACM91587 ACM91588 BAG34911 CAA23777 CAG33708 EAW48613 EAW48614

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca