Version 5.4
Homo sapiens Protein: IL28RA
Summary
InnateDB Protein IDBP-94163.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL28RA
Protein Name interleukin 28 receptor, alpha (interferon, lambda receptor)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000363542
InnateDB Gene IDBG-94157 (IL28RA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0002385 mucosal immune response
GO:0008285 negative regulation of cell proliferation
GO:0019221 cytokine-mediated signaling pathway
GO:0034342 response to type III interferon
GO:0050691 regulation of defense response to virus by host
GO:0051607 defense response to virus
Cellular Component
GO:0016021 integral component of membrane
GO:0032002 interleukin-28 receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
PFAM PF00041
PF01108
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IU57
PhosphoSite PhosphoSite-Q8IU57
TrEMBL
UniProt Splice Variant
Entrez Gene 163702
UniGene Hs.619077
RefSeq NP_775087
HUGO HGNC:18584
OMIM 607404
CCDS CCDS249
HPRD 09589
IMGT
EMBL AF439325 AJ534330 AJ534331 AK160364 AL590683 AY129151 AY129152 AY129153 BC140872 CH471134
GenPept AAI40873 AAN28266 AAN28267 AAN28268 AAN63632 BAD18707 CAD58829 CAD58830 CAH70118 CAH70119 CAH70120 CAH70121 EAW95114 EAW95115 EAW95117 EAW95118

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca