InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SYF2

Summary

InnateDB Protein

IDBP-94278.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SYF2

Protein Name

SYF2 homolog, RNA splicing factor (S. cerevisiae)

Synonyms

CBPIN; fSAP29; NTC31; P29;

Species

Homo sapiens

Ensembl Protein

ENSP00000236273

InnateDB Gene

IDBG-94274 (SYF2)

Protein Structure

UniProt Annotation

Function

May be involved in pre-mRNA splicing. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:11118353}.

Disease Associations

Tissue Specificity

Abundantly expressed in the heart, skeletal muscle and kidney. Expressed at lower level other tissues. {ECO:0000269PubMed:11118353}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000398	mRNA splicing, via spliceosome
GO:0001701	in utero embryonic development
GO:0007095	mitotic G2 DNA damage checkpoint
GO:0007369	gastrulation
GO:0048568	embryonic organ development

Cellular Component

GO:0005634	nucleus
GO:0071013	catalytic step 2 spliceosome

Protein Structure and Domains

PDB ID

InterPro

IPR013260 mRNA splicing factor SYF2

PFAM

PF08231

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O95926

PhosphoSite

PhosphoSite-O95926

TrEMBL

UniProt Splice Variant

Entrez Gene

25949

UniGene

Hs.594135

RefSeq

NP_056299

HUGO

HGNC:19824

OMIM

607090

CCDS

CCDS259

HPRD

07386

IMGT

EMBL

AF273089 AL031432 AL080166 BC010862

GenPept

AAG42073 AAH10862 CAB37991 CAB45754 CAI21417