InnateDB Protein
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IDBP-94977.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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IFI6
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Protein Name
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interferon, alpha-inducible protein 6
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Synonyms
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6-16; FAM14C; G1P3; IFI-6-16; IFI616;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000354736
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InnateDB Gene
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IDBG-94975 (IFI6)
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Protein Structure
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Function |
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Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
11
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
10
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0001836
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release of cytochrome c from mitochondria
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GO:0006955
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immune response
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GO:0019221
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cytokine-mediated signaling pathway
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GO:0043154
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negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
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GO:0045087
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innate immune response (InnateDB)
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GO:0051902
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negative regulation of mitochondrial depolarization
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GO:0060337
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type I interferon signaling pathway
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GO:2001240
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negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
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Cellular Component |
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PDB ID |
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InterPro |
IPR009311
Interferon alpha-inducible protein 6/27
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PFAM |
PF06140
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P09912
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
2537
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UniGene |
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RefSeq |
NP_002029
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HUGO |
HGNC:4054
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OMIM |
147572
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CCDS |
CCDS306
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HPRD |
00959
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IMGT |
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EMBL |
AK314488
AL445490
BC011601
BC015603
BN000257
BT006850
CH471059
U22970
X02492
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GenPept |
AAC50159
AAC50160
AAC50161
AAH11601
AAH15603
AAP35496
BAG37089
CAA26322
CAE12275
CAH72020
CAH72021
CAH72022
EAX07744
EAX07745
EAX07746
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