Homo sapiens Protein: EYA3
Summary
InnateDB Protein IDBP-95143.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EYA3
Protein Name eyes absent homolog 3 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362970
InnateDB Gene IDBG-95137 (EYA3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006302 double-strand break repair
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0007601 visual perception
GO:0009653 anatomical structure morphogenesis
GO:0010212 response to ionizing radiation
GO:0016576 histone dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0045739 positive regulation of DNA repair
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR006545 EYA domain
IPR023214 HAD-like domain
PFAM PF00702
PF08282
PF13419
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99504
PhosphoSite PhosphoSite-Q99504
TrEMBL
UniProt Splice Variant
Entrez Gene 2140
UniGene Hs.185774
RefSeq NP_001269489
HUGO HGNC:3521
OMIM 601655
CCDS CCDS60052
HPRD 09042
IMGT
EMBL AJ007991 AK289805 AK295745 AK298129 AL137792 AL512288 BC041667 CH471059 U81602 Y10262
GenPept AAB42066 AAH41667 BAF82494 BAG58579 BAG60409 CAA07814 CAA71311 CAI14297 EAX07713 EAX07714