InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MATN1

Summary

InnateDB Protein

IDBP-95363.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MATN1

Protein Name

matrilin 1, cartilage matrix protein

Synonyms

CMP; CRTM;

Species

Homo sapiens

Ensembl Protein

ENSP00000362870

InnateDB Gene

IDBG-95361 (MATN1)

Protein Structure

UniProt Annotation

Function

Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.

Subcellular Localization

Secreted, extracellular space, extracellular matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005201	extracellular matrix structural constituent
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0002062	chondrocyte differentiation
GO:0003429	growth plate cartilage chondrocyte morphogenesis
GO:0006461	protein complex assembly
GO:0030198	extracellular matrix organization
GO:0030500	regulation of bone mineralization

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR002035 von Willebrand factor, type A
IPR019466 Matrilin, coiled-coil trimerisation domain

PFAM

PF00008
PF07645
PF00092
PF10393

PRINTS

PIRSF

SMART

SM00181
SM00179
SM00327

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P21941