InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SNRNP40

Summary

InnateDB Protein

IDBP-95413.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNRNP40

Protein Name

small nuclear ribonucleoprotein 40kDa (U5)

Synonyms

40K; HPRP8BP; PRP8BP; PRPF8BP; SPF38; WDR57;

Species

Homo sapiens

Ensembl Protein

ENSP00000263694

InnateDB Gene

IDBG-95411 (SNRNP40)

Protein Structure

UniProt Annotation

Function

Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs. {ECO:0000269PubMed:9774689}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:9731529}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.

Experimentally validated
Total	49 [view]
Protein-Protein	46 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000375	RNA splicing, via transesterification reactions
GO:0000398	mRNA splicing, via spliceosome
GO:0006396	RNA processing
GO:0008380	RNA splicing
GO:0010467	gene expression

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005682	U5 snRNP
GO:0005732	small nucleolar ribonucleoprotein complex
GO:0005737	cytoplasm
GO:0071013	catalytic step 2 spliceosome