Version 5.4
Homo sapiens Gene: SNRNP40
Summary
InnateDB Gene IDBG-95411.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNRNP40
Gene Name small nuclear ribonucleoprotein 40kDa (U5)
Synonyms 40K; HPRP8BP; PRP8BP; PRPF8BP; SPF38; WDR57
Species Homo sapiens
Ensembl Gene ENSG00000060688
Encoded Proteins
IDBP-95413
small nuclear ribonucleoprotein 40kDa (U5)
IDBP-95415
small nuclear ribonucleoprotein 40kDa (U5)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:31259568-31296782
Strand Reverse strand
Band p35.2
Transcripts
ENST00000263694 ENSP00000263694
ENST00000373720 ENSP00000362825
ENST00000486941
ENST00000489853
ENST00000491106
ENST00000474025
ENST00000463988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
Experimentally validated
Total 49 [view]
Protein-Protein 46 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000375 RNA splicing, via transesterification reactions
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0008380 RNA splicing
GO:0010467 gene expression
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005682 U5 snRNP
GO:0005732 small nucleolar ribonucleoprotein complex
GO:0005737 cytoplasm
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000074088
View Gene Order
ENSBTAG00000016817
Not yet available
Pathways
NETPATH
REACTOME
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_1753
mRNA Splicing - Minor Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.33962
RefSeq NM_004814
HUGO
OMIM
CCDS CCDS340
HPRD 08481
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca