Version 5.4
Homo sapiens Protein: FABP3
Summary
InnateDB Protein IDBP-95444.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FABP3
Protein Name fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
Synonyms FABP11; H-FABP; M-FABP; MDGI; O-FABP;
Species Homo sapiens
Ensembl Protein ENSP00000362817
InnateDB Gene IDBG-95442 (FABP3)
Protein Structure
UniProt Annotation
Function FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005324 long-chain fatty acid transporter activity
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0036041 long-chain fatty acid binding
GO:0050543 icosatetraenoic acid binding
GO:0070538 oleic acid binding
Biological Process
GO:0006631 fatty acid metabolic process
GO:0008285 negative regulation of cell proliferation
GO:0015909 long-chain fatty acid transport
GO:0032868 response to insulin
GO:0042493 response to drug
GO:0042632 cholesterol homeostasis
GO:0044539 long-chain fatty acid import
GO:0046320 regulation of fatty acid oxidation
GO:0055091 phospholipid homeostasis
GO:0070542 response to fatty acid
GO:0071073 positive regulation of phospholipid biosynthetic process
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016528 sarcoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000463 Cytosolic fatty-acid binding
IPR000566 Lipocalin/cytosolic fatty-acid binding domain
IPR011038 Calycin-like
PFAM PF00061
PF08212
PRINTS PR00178
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P05413
PhosphoSite PhosphoSite-P05413
TrEMBL S4R371
UniProt Splice Variant
Entrez Gene 2170
UniGene
RefSeq NP_004093
HUGO HGNC:3557
OMIM 134651
CCDS CCDS342
HPRD 00613
IMGT
EMBL AK314122 AL451070 BC007021 BT006727 CH471059 S67314 U17081 U57623 X56549 Y10255
GenPept AAB02555 AAB29294 AAC99800 AAH07021 AAP35373 BAG36813 CAA39889 CAA71305 CAH71850 EAX07619

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca