Version 5.4
Homo sapiens Protein: SYNC
Summary
InnateDB Protein IDBP-95792.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNC
Protein Name syncoilin, intermediate filament protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362583
InnateDB Gene IDBG-95790 (SYNC)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm, perinuclear region {ECO:0000250UniProtKB:Q9EPM5}. Note=In skeletal muscle, colocalizes with DES and DTNA, and is localized at the myotendinous and neuromuscular junctions, sarcolemma and Z-lines. In myotubes, detected in a punctate cytoplasmic pattern (By similarity). {ECO:0000250UniProtKB:Q9EPM5}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
Cellular Component
GO:0005882 intermediate filament
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001664 Intermediate filament protein
PFAM PF00038
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H7C4
PhosphoSite PhosphoSite-Q9H7C4
TrEMBL C9JTN4
UniProt Splice Variant
Entrez Gene 81493
UniGene
RefSeq NP_001155180
HUGO HGNC:28897
OMIM 611750
CCDS CCDS53294
HPRD 18134
IMGT
EMBL AC114489 AK024707 AK297958 AK302275 BC119700 BC119701
GenPept AAI19701 AAI19702 BAB14970 BAG60270 BAG63620

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca