InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CAP1

Summary

InnateDB Protein

IDBP-96845.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CAP1

Protein Name

CAP, adenylate cyclase-associated protein 1 (yeast)

Synonyms

CAP; CAP1-PEN;

Species

Homo sapiens

Ensembl Protein

ENSP00000361883

InnateDB Gene

IDBG-96837 (CAP1)

Protein Structure

UniProt Annotation

Function

Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.

Subcellular Localization

Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	44 [view]
Protein-Protein	43 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding

Biological Process

GO:0000902	cell morphogenesis
GO:0001667	ameboidal cell migration
GO:0002576	platelet degranulation
GO:0006898	receptor-mediated endocytosis
GO:0007010	cytoskeleton organization
GO:0007163	establishment or maintenance of cell polarity
GO:0007165	signal transduction
GO:0007190	activation of adenylate cyclase activity
GO:0007411	axon guidance
GO:0007596	blood coagulation
GO:0030036	actin cytoskeleton organization
GO:0030168	platelet activation