InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CYP2D6

Summary

InnateDB Protein

IDBP-9692.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYP2D6

Protein Name

cytochrome P450, family 2, subfamily D, polypeptide 6

Synonyms

CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; P450-DB1; P450C2D; P450DB1;

Species

Homo sapiens

Ensembl Protein

ENSP00000351927

InnateDB Gene

IDBG-9690 (CYP2D6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004497	monooxygenase activity
GO:0005506	iron ion binding
GO:0008144	drug binding
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding
GO:0070330	aromatase activity

Biological Process

GO:0006805	xenobiotic metabolic process
GO:0008202	steroid metabolic process
GO:0009804	coumarin metabolic process
GO:0009820	alkaloid metabolic process
GO:0009822	alkaloid catabolic process
GO:0016098	monoterpenoid metabolic process
GO:0017144	drug metabolic process
GO:0033076	isoquinoline alkaloid metabolic process
GO:0042737	drug catabolic process
GO:0044281	small molecule metabolic process
GO:0046483	heterocycle metabolic process
GO:0051100	negative regulation of binding
GO:0055114	oxidation-reduction process
GO:0070989	oxidative demethylation
GO:0090350	negative regulation of cellular organofluorine metabolic process