Version 5.4
Homo sapiens Protein: IL20RA
Summary
InnateDB Protein IDBP-96989.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL20RA
Protein Name interleukin 20 receptor, alpha
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000356722
InnateDB Gene IDBG-96985 (IL20RA)
Protein Structure
UniProt Annotation
Function The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin. {ECO:0000269PubMed:11163236, ECO:0000269PubMed:14764663}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
IPR015373 Interferon alpha/beta receptor, beta chain
PFAM PF00041
PF01108
PF09294
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UHF4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 53832
UniGene Hs.734385
RefSeq NP_001265653
HUGO HGNC:6003
OMIM 605620
CCDS CCDS64535
HPRD 05729
IMGT
EMBL AF184971 AK297121 AL135902 AY358883 BC113574 BC113602 CH471051
GenPept AAF01320 AAI13575 AAI13603 AAQ89242 BAG59627 CAC38375 EAW47936

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca