InnateDB Protein
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IDBP-97659.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC6A9
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Protein Name
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solute carrier family 6 (neurotransmitter transporter, glycine), member 9
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Synonyms
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GLYT1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000353791
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InnateDB Gene
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IDBG-97649 (SLC6A9)
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Protein Structure
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Function |
Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Isoform GlyT-1A and isoform GlyT-1B can be found in brain, kidney, pancreas, lung, placenta and liver but isoform GlyT-1C is only found in brain.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000175
Sodium:neurotransmitter symporter
IPR003028
Sodium:neurotransmitter symporter, glycine, type 1
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PFAM |
PF00209
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PRINTS |
PR00176
PR01204
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P48067
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PhosphoSite |
PhosphoSite-P48067
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TrEMBL |
B7Z589
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UniProt Splice Variant |
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Entrez Gene |
6536
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UniGene |
Hs.742306
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RefSeq |
NP_964012
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HUGO |
HGNC:11056
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OMIM |
601019
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CCDS |
CCDS41317
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HPRD |
03010
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IMGT |
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EMBL |
AK298611
AL139220
CH471059
S70609
S70612
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GenPept |
AAB30784
AAB30785
BAH12825
CAI19428
CAI19429
CAI19430
EAX07056
EAX07057
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