InnateDB Protein
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IDBP-97803.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BEST4
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Protein Name
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bestrophin 4
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000361281
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InnateDB Gene
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IDBG-97801 (BEST4)
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Protein Structure
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Function |
Forms calcium-sensitive chloride channels. Permeable to bicarbonate. {ECO:0000269PubMed:12907679, ECO:0000269PubMed:18400985}.
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Subcellular Localization |
Cell membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Predominantly found in colon and the weakly in fetal brain, spinal cord, retina, lung, trachea, testis and placenta. {ECO:0000269PubMed:12032738}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR021134
Bestrophin/UPF0187
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PFAM |
PF01062
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NFU0
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PhosphoSite |
PhosphoSite-Q8NFU0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
266675
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UniGene |
Hs.302513
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RefSeq |
NP_695006
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HUGO |
HGNC:17106
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OMIM |
607336
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CCDS |
CCDS514
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HPRD |
09549
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IMGT |
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EMBL |
AF440757
AL592166
AY515707
BC101823
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GenPept |
AAI01824
AAM76996
AAR99657
CAI13005
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