Version 5.4
Homo sapiens Protein: MTRF1L
Summary
InnateDB Protein IDBP-98159.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTRF1L
Protein Name mitochondrial translational release factor 1-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000356200
InnateDB Gene IDBG-98155 (MTRF1L)
Protein Structure
UniProt Annotation
Function Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG. {ECO:0000269PubMed:17803939}.
Subcellular Localization Mitochondrion {ECO:0000269PubMed:17803939}.
Disease Associations
Tissue Specificity Expressed in skeletal muscle (at protein level). {ECO:0000269PubMed:17803939}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006415 translational termination
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR000352 Peptide chain release factor class I/class II
IPR005139 Peptide chain release factor
PFAM PF00472
PF03462
PRINTS
PIRSF
SMART SM00937
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UGC7
PhosphoSite PhosphoSite-Q9UGC7
TrEMBL
UniProt Splice Variant
Entrez Gene 54516
UniGene Hs.721577
RefSeq NP_001107656
HUGO HGNC:21051
OMIM 613542
CCDS CCDS47502
HPRD 17613
IMGT
EMBL AK027684 AK095240 AK290662 AL080276 BC011873 BC014428 BC105973 CH471051
GenPept AAH11873 AAH14428 AAI05974 BAB55295 BAF83351 BAG53012 CAB65994 CAI18897 CAI18898 CAI18899 EAW47712

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca