Homo sapiens Protein: CYP4B1 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-98193.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | CYP4B1 | ||||||||||||
Protein Name | cytochrome P450, family 4, subfamily B, polypeptide 1 | ||||||||||||
Synonyms | CYPIVB1; P-450HP; | ||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Protein | ENSP00000271153 | ||||||||||||
InnateDB Gene | IDBG-98187 (CYP4B1) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | ||||||||||||
Subcellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | Detected in the liver and lung (at protein level). {ECO:0000269PubMed:12695542}. | ||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | |||||||||||||
InterPro |
IPR001128
Cytochrome P450 IPR002401 Cytochrome P450, E-class, group I IPR002402 Cytochrome P450, E-class, group II IPR002403 Cytochrome P450, E-class, group IV |
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PFAM |
PF00067
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PRINTS |
PR00385
PR00463 PR00464 PR00465 |
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PIRSF | |||||||||||||
SMART | |||||||||||||
TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | P13584 | ||||||||||||
PhosphoSite | PhosphoSite-P13584 | ||||||||||||
TrEMBL | F5H6F1 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 1580 | ||||||||||||
UniGene | Hs.738634 | ||||||||||||
RefSeq | NP_000770 | ||||||||||||
HUGO | HGNC:2644 | ||||||||||||
OMIM | 124075 | ||||||||||||
CCDS | CCDS542 | ||||||||||||
HPRD | 00491 | ||||||||||||
IMGT | |||||||||||||
EMBL | AF491285 AK300921 AL356793 AL593856 AY064485 AY064486 AY151048 BC017758 DQ518907 J02871 X16699 | ||||||||||||
GenPept | AAA35712 AAH17758 AAL57720 AAL57721 AAM09532 AAN72311 ABF47106 BAG62553 CAA34672 CAI16981 CAI16982 CAI22557 CAI22559 | ||||||||||||