Version 5.4
Homo sapiens Protein: EPS15
Summary
InnateDB Protein IDBP-98488.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EPS15
Protein Name epidermal growth factor receptor pathway substrate 15
Synonyms AF-1P; AF1P; MLLT5;
Species Homo sapiens
Ensembl Protein ENSP00000360795
InnateDB Gene IDBG-98484 (EPS15)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 151 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 151 [view]
Protein-Protein 150 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR000261 EPS15 homology (EH)
IPR002048 EF-hand domain
IPR003903 Ubiquitin interacting motif
PFAM PF00036
PF13202
PF13405
PF02809
PRINTS
PIRSF
SMART SM00027
SM00054
SM00726
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1AUU8
UniProt Splice Variant
Entrez Gene 2060
UniGene Hs.83722
RefSeq
HUGO HGNC:3419
OMIM 600051
CCDS
HPRD 08968
IMGT
EMBL AC104170 AL671986
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca