Version 5.4
Homo sapiens Protein: SRSF11
Summary
InnateDB Protein IDBP-99640.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRSF11
Protein Name serine/arginine-rich splicing factor 11
Synonyms dJ677H15.2; NET2; p54; SFRS11;
Species Homo sapiens
Ensembl Protein ENSP00000359988
InnateDB Gene IDBG-99636 (SRSF11)
Protein Structure
UniProt Annotation
Function May function in pre-mRNA splicing.
Subcellular Localization Nucleus. Note=Colocalizes with spliceosome components.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 64 experimentally validated interaction(s) in this database.
Experimentally validated
Total 64 [view]
Protein-Protein 59 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006366 transcription from RNA polymerase II promoter
GO:0006369 termination of RNA polymerase II transcription
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0031124 mRNA 3'-end processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q05519
PhosphoSite PhosphoSite-Q05519
TrEMBL Q6N079
UniProt Splice Variant
Entrez Gene 9295
UniGene Hs.628182
RefSeq NP_004759
HUGO HGNC:10782
OMIM 602010
CCDS CCDS647
HPRD 03599
IMGT
EMBL AL353771 BC040436 BX640645 CH471059 M74002
GenPept AAA35554 AAH40436 CAE45791 CAI22334 CAI22335 EAX06459

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca