Homo sapiens Gene: FRRS1
Summary
InnateDB Gene IDBG-100446.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FRRS1
Gene Name ferric-chelate reductase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000156869
Encoded Proteins
ferric-chelate reductase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the cytochrome b561 (CYB561; MIM 600019) family, including FRRS1, reduce ferric to ferrous iron before its transport from the endosome to the cytoplasm (Vargas et al., 2003 [PubMed 14499595]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:99708703-99766631
Strand Reverse strand
Band p21.2
Transcripts
ENST00000287474 ENSP00000287474
ENST00000370176
ENST00000489209
ENST00000492943
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000293 ferric-chelate reductase activity
GO:0046872 metal ion binding
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.454779
RefSeq NM_001013660
HUGO
OMIM
CCDS CCDS30780
HPRD 18403
IMGT
EMBL
GenPept
RNA Seq Atlas