Version 5.4
Homo sapiens Gene: POLDIP3
Summary
InnateDB Gene IDBG-10097.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLDIP3
Gene Name polymerase (DNA-directed), delta interacting protein 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100227
Encoded Proteins
IDBP-10099
polymerase (DNA-directed), delta interacting protein 3
IDBP-10101
polymerase (DNA-directed), delta interacting protein 3
IDBP-10103
polymerase (DNA-directed), delta interacting protein 3
IDBP-378911
polymerase (DNA-directed), delta interacting protein 3
IDBP-378914
polymerase (DNA-directed), delta interacting protein 3
IDBP-378918
polymerase (DNA-directed), delta interacting protein 3
IDBP-807333
polymerase (DNA-directed), delta interacting protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:42583721-42614962
Strand Reverse strand
Band q13.2
Transcripts
ENST00000252115 ENSP00000252115
ENST00000348657 ENSP00000252116
ENST00000339677 ENSP00000343060
ENST00000445215 ENSP00000415234
ENST00000451060 ENSP00000397927
ENST00000454057 ENSP00000408046
ENST00000491021
ENST00000463133
ENST00000617178 ENSP00000482500
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0016973 poly(A)+ mRNA export from nucleus
GO:0045727 positive regulation of translation
Cellular Component
GO:0000346 transcription export complex
GO:0005737 cytoplasm
GO:0016607 nuclear speck
GO:0035145 exon-exon junction complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041815
View Gene Order
ENSBTAG00000016511
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
mtor_4pathway
mTOR signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.505802 Hs.743592
RefSeq NM_001278657 NM_032311 NM_178136
HUGO
OMIM
CCDS CCDS14038 CCDS14039 CCDS74873
HPRD 17875
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca