Version 5.4
| Homo sapiens Gene: KCNA10 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-100987.5 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | KCNA10 | ||||||||||||||||||
| Gene Name | potassium voltage-gated channel, shaker-related subfamily, member 10 | ||||||||||||||||||
| Synonyms | Kcn1; Kv1.8 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000143105 | ||||||||||||||||||
| Encoded Proteins |
potassium voltage-gated channel, shaker-related subfamily, member 10
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 1:110517251-110518838 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | p13.3 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Voltage gated Potassium channels pathway
Neuronal System pathway
Potassium Channels pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | Q16322 | ||||||||||||||||||
| TrEMBL | Q7KYZ7 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 3744 | ||||||||||||||||||
| UniGene | Hs.248140 Hs.622910 | ||||||||||||||||||
| RefSeq | NM_005549 | ||||||||||||||||||
| HUGO | HGNC:6219 | ||||||||||||||||||
| OMIM | 602420 | ||||||||||||||||||
| CCDS | CCDS826 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AL358215 BC074990 CH471122 S77547 U96110 | ||||||||||||||||||
| GenPept | AAB34663 AAC51333 AAH74990 CAH74103 EAW56454 | ||||||||||||||||||
| RNA Seq Atlas | 3744 | ||||||||||||||||||