Homo sapiens Gene: HSD3B1
Summary
InnateDB Gene IDBG-101508.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSD3B1
Gene Name hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Synonyms 3BETAHSD; HSD3B; HSDB3; HSDB3A; I; SDR11E1;
Species Homo sapiens
Ensembl Gene ENSG00000203857
Encoded Proteins
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:119507198-119515054
Strand Forward strand
Band p12
Transcripts
ENST00000369413 ENSP00000358421
ENST00000492140
ENST00000487520
ENST00000531340 ENSP00000435999
ENST00000528909 ENSP00000432268
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0004769 steroid delta-isomerase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662 coenzyme binding
Biological Process
GO:0006694 steroid biosynthetic process
GO:0006702 androgen biosynthetic process
GO:0006703 estrogen biosynthetic process
GO:0006704 glucocorticoid biosynthetic process
GO:0006705 mineralocorticoid biosynthetic process
GO:0008152 metabolic process
GO:0008202 steroid metabolic process
GO:0009058 biosynthetic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0030868 smooth endoplasmic reticulum membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Metabolism of lipids and lipoproteins pathway
Mineralocorticoid biosynthesis pathway
Metabolism of steroid hormones and vitamin D pathway
Androgen biosynthesis pathway
Metabolism pathway
Glucocorticoid biosynthesis pathway
KEGG
Steroid hormone biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P14060
TrEMBL E9PRN7 Q5TDG2
UniProt Splice Variant
Entrez Gene 3283
UniGene
RefSeq NM_000862
HUGO HGNC:5217
OMIM 109715
CCDS CCDS903
HPRD 04920
IMGT
EMBL AK291556 AL121995 BC031999 M27137 M28162 M28391 M28392 M35493 M38180 M63395 M63396 M63397 S45679 X53321 X55997
GenPept AAA36001 AAA36015 AAA51538 AAA51662 AAA51831 AAB23543 AAH31999 BAF84245 CAA37408 CAA39469
RNA Seq Atlas 3283